金芳芳(邮箱:ffjin@njucm.edu.cn ),南京大学生物学博士,副教授,硕士生导师。主要从事非编码小RNA与肿瘤、自身性免疫等疾病的诊断、发病机制及治疗方向的研究。主持国自然青年基金、江苏省青年基金等项目共5项;入选2020年江苏省“双创博士”;承担生化与分子实验等课程的教学工作。
代表性论文:
1)Zhan S*, Yang P*, Zhou S*, Xu Y, Xu R, Liang G, Zhang C, Chen X, Yang L#, Jin F#, Wang Y#. Serum mitochondrial tsRNA serves as a novel biomarker for hepatocarcinoma diagnosis. Front Med-Prc. 2022.Accepted.
2)Jin F*, Yang L*, Wang W*, Yuan N, Zhan S, Yang P, Chen X#, Ma T#, Wang Y#. A novel class of tsRNA signatures as biomarkers for diagnosis and prognosis of pancreatic cancer. Mol Cancer. 2021 Jul 17;20(1):95.
3)Jin F*, Yang R*, Wei Y*, Wang D, Zhu Y, Wang X, Lu Y, Wang Y#, Zen K#, Li L#. HIF-1α-induced miR-23a∼27a∼24 cluster promotes colorectal cancer progression via reprogramming metabolism. Cancer Lett. 2019 Jan; 440-441:211-222.
4)Wang Y*, Liang H*, Jin F*, Yan X*, Xu G, Hu H, Liang G, Zhan S, Hu X, Zhao Q, Liu Y, Jiang ZY, Zhang CY#, Chen X#, Zen K#. Injured liver-released miRNA-122 elicits acute pulmonary inflammation via activating alveolar macrophage TLR7 signaling pathway. Proc Natl Acad Sci U SA. 2019 Mar 26; 116(13):6162-6171.
5)Jin F*, Guo Z#. Emerging role of a novel small non-coding regulatory RNA: tRNA-derived small RNA. ExRNA. 2019 1:39.
6)Jin F#, Sun Y. Identification and characterization of salt-tolerance relative miRNAs in Procambarus clarkii by high-throughput sequencing. ExRNA. 2019 1:18.
7)Jin F*, Hu H*, Xu M*, Zhan S, Wang Y#, Zhang H#, Chen X#. Serum microRNA Profiles Serve as Novel Biomarkers for Autoimmune Diseases. Front Immunol. 2018 Oct 16; 9:2381.
8)Jin F*, Wang Y*, Li M, Zhu Y, Liang H, Wang C, Wang F, Zhang CY#, Zen K#, Li L#. Cell Death Dis. 2017 Jan 12;8(1):e2540.
9)Wei Y*, Wang D*, Jin F*, Bian Z*, Li L, Liang H, Li M, Shi L, Pan C, Zhu D, Chen X, Hu G#, Liu Y#, Zhang CY#, Zen K#. Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23. Nat Commun. 2017 Jan 9;8:14041.
10)Jin F*, Wang Y*, Zhu Y*, Li S, Liu Y, Chen C, Wang X#, Zen K#, Li L#. The miR-125a/HK2 axis regulates cancer cell energy metabolism reprogramming in hepatocellular carcinoma. Sci Rep. 2017 Jun 8;7(1):3089.
11)Li L*, Zhang T*, Diao W*, Jin F*, Shi L, Meng J, Liu H, Zhang J, Zeng CH, Zhang MC, Liang S, Liu Y, Zhang CY#, Liu Z#, Zen K#. Role of Myeloid-Derived Suppressor Cells in Glucocorticoid-Mediated Amelioration of FSGS. J Am Soc Nephrol. 2015 Sep;26(9):2183-97.