王冰微

王冰微（邮箱：bingweiwang@njucm.edu.cn），博士，副教授，硕士生导师

主要从事神经退行性疾病相关的神经生物学与神经免疫学研究。

近年代表性通讯研究论文

1. Li, S.#, Wu, Y.#, Yang, D., Wu, C., Ma, C., Liu, X., Moynagh, P.N., Wang, B.*, Hu, G.*, Yang,S.* Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis. Journal of Experimental Medicine (F1000Prime). 2019 Nov 4; 216(11):2562-2581; doi: 10.1084/jem.20190377. 

2. Wu, Y.#, Hu, Y.#, Wang, B.#*, Li, S., Ma, C., Liu, X., Moynagh, P.N., Zhou, J., and Yang, S.* Dopamine uses the DRD5-ARRB2-PP2A signalling axis to block the TRAF6-mediated NF-B pathway and suppress systemic inflammation. Molecular cell. 2020 April 2; 78: 1–15. 

3. Yang, S.#, Wang, B.#, Humphries, F., Hogan, A.E., O’Shea, D., Moynagh, P.N.* The E3 ubiquitin ligase Pellino3 protects against obesity-induced inflammation and insulin resistance. Immunity. 2014 Dec 18; 41(6):973-87; doi:10.1016/　j.immuni.2014.11.013. 

4. Yang, S., Wang, B., Tang, L.S., Siednienko, J., Callanan, J.J., Moynagh, P.N. Pellino3 targets RIP1 and regulates the pro-apoptotic effects of TNF-α. (2013) Nature Communications 4:2583

5. Yang, S., Wang, B., Humphries, F., Jackson, R., Healy, M.E., Bergin, R., Aviello, G., Hall, B., McNamara, D., Darby, T., Quinlan, A., Shanahan, F., Melgar, S., Fallon, P.G., Moynagh, P.N. Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis. (2013) Nature Immunology 14(9):927–936

6.   Siednienko, J., Jackson, R., Mellett, M., Delagic, N., Yang, S., Wang, B., Tang, L.S., Callanan, J.J., Moynagh, P.N. Pellino3 targets the IRF7 pathway and facilitates autoregulation of TLR3-and viral-induced expression of type I interferons. (2012) Nature Immunology 13 (11) PP.1055–1062; doi: 10.1038/ni.2429 (IF: 26.19)