张园娇（邮箱：zyj494@njucm.edu.cn），博士，副教授，硕士生导师，现任澳门新莆京5088app官网学院专任教师，澳门新莆京5088app官网校C类特聘引进人才。

主要从事多发性骨髓瘤的靶点发现与干预研究。主持国家自然科学基金青年项目1项、澳门新莆京5088app官网特聘教授配套项目1项，参与1项国家重点研发计划课题和多项国家自然科学基金面上项目。以第一及共同一作身份在Signal Transduction and Targeted Therapy、Clinical and Translational Medicine、Cancer communications等国际知名期刊发表SCI论文数篇，单篇最高影响因子为39.3；指导本科生获得全国大学生基础医学创新研究大赛三等奖。

代表性研究论文

1.Yuanjiao Zhang; Jinjun Qian; Chunyan Gu#; Ye Yang#. Alternative splicing and cancer: a systematic review, Signal Transduction and Targeted Therapy, 2021, 6:78. （医学一区，IF：39.3）

2.Yuanjiao Zhang; Xichao Yu; Rongze Sun; Jie Min; Xiaozhu Tang; Zigen Lin; Siyuan Xie; Xinying Li; Shengfeng Lu; Zhidan Tian; Chunyan Gu#; Lesheng Teng#; Ye Yang#. Splicing factor arginine/serine-rich 8 promotes multiple myeloma malignancy and bone lesion through alternative splicing of CACYBP and exosome-based cellular communication, Clinical and Translational Medicine, 2022;12(2):e684.（医学一区，IF：10.6）

3.Rongfang Wei; Yan Zhu; Yuanjiao Zhang (co-first author); Wene Zhao; Xichao Yu; Ling Wang; Chunyan Gu#, Xiaosong Gu#, Ye Yang#. AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation, Cancer Communications, 2022, 1:22. （医学一区，IF：15.283）

4.Yuanjiao Zhang; Zhendong Deng; Shanliang Sun; Siyuan Xie; Mingmei Jiang; Bing Chen#; Chunyan Gu#; Ye Yang#. NAT10 acetylates BCL-XL mRNA to promote the proliferation of multiple myeloma cells through PI3K-AKT pathway, Frontiers in oncology, 2022;12:967811.（医学二区，IF：4.7）

5.Yuanjiao Zhang; Jiacheng Qian; Mingmei Jiang; Shu Yang; Lianxin Zhou; Qin Zhang#; Liping Lin#; Ye Yang#. LTe2 induces cell apoptosis in multiple myeloma by suppressing AKT phosphorylation at Thr308 and Ser473. Frontiers in oncology, 2023;13:1269670.（医学二区，IF：4.7）