于小轩(邮箱:xxyu@njucm.edu.cn), 博士,副教授,硕士生研究生导师,现任澳门新莆京5088app官网药理学系专任教师,澳门新莆京5088app官网校C类特聘引进人才,中华中医药学会会员。
主要从事白血病免疫治疗的探索及其药物干预研究。先后主持国家级与省部级自然科学基金课题5项,相关研究成果发表SCI学术论文10余篇 ,授权专利1项,主参编《食品生物技术实验》。目前担任Journal of Translational Medicine, Heliyon学术杂志审稿专家。
代表性研究论文
(1) Xiaoxuan Yu#; Hui Li#; Po Hu; Yingjie Qing; Xiangyuan Wang; Mengyuan Zhu; Hongzheng Wang; Zhanyu Wang; Jingyan Xu; Qinglong Guo; Hui Hui ; Natural HDAC-1/8 inhibitor baicalein exerts therapeutic effect in CBF-AML, Clinical and translational medicine, 2020, 10(4): e154
(2) Xiaoxuan Yu#; Meng-yuan Zhu#; Jia-rong Wang; Hui Li; Po Hu; Ying-jie Qing; Xiang-yuan Wang; Hong-zheng Wang; Zhan-yu Wang; Jing-yan Xu; Qing-long Guo; Hui Hui ; LW-213 induces cell apoptosis in human cutaneous T-cell lymphomas by activating PERK–eIF2α–ATF4–CHOP axis, Acta Pharmacologica Sinica, 2021, Feb(42(2)): 290-300
(3) Xiaoxuan Yu#; Hui Li#; Mengyuan Zhu; Po Hu; Xiao Liu; Yingjie Qing; Xiangyuan Wang; Hongzheng Wang; Zhanyu Wang; Jingyan Xu; Renxiang Tan; Qinglong Guo; Hui Hui ; Involvement of p53 acetylation in growth suppression of Cutaneous T-cell lymphomas induced by HDAC inhibition, Journal of investigative dermatology, 2020, 140(10): 2009-2022
(4) Hui Li#; Xiaoxuan Yu#; Xiao Liu; Po Hu; Le Shen; Yuxin Zhou; Yu Zhu; Zhiyu Li; Hui Hui; Qinglong Guo; Jingyan Xu ; Wogonoside induces depalmitoylation and translocation of PLSCR1 and N‐RAS in primary acute myeloid leukaemia cells, Journal of cellular and molecular medicine, 2018, 22(4): 2117-2130
(5) Hu Po#; Hui Li#; Xiaoxuan Yu; Xiao Liu; Xiangyuan Wang; Yingjie Qing; Zhanyu Wang; Hongzheng Wang; Mengyuan Zhu; Jingyan Xu; Renxiang Tan; Qinglong Guo; Hui Hui ; GL-V9 exerts anti-T cell malignancies effects via promoting lysosome-dependent AKT1 degradation and activating AKT1/FOXO3A/BIM axis, Free Radical Biology & Medicine, 2019, Dec(145): 237-249